SCHEMBL16124672

SCHEMBL16124672

CCCCCCCOC(=O)CC(N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.56
NOD1 Q9Y239 2/20 0.53
P2RY10 O00398 5/20 0.52
GPR34 Q9UPC5 2/20 0.52
GRIK1 P39086 2/20 0.51
GRIK2 Q13002 2/20 0.51
HTR2C P28335 1/20 0.50
SLC1A2 P43004 1/20 0.49
SLC1A1 P43005 1/20 0.49
RAD52 P43351 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
FAAH O00519 1/20 0.47
DGKA P23743 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7918479 1.00 NAAA (0.56) NAAANOD1P2RY10GPR34GRIK1
SCHEMBL7781906 1.00 NAAA (0.56) NAAANOD1P2RY10GPR34GRIK1
SCHEMBL7775094 1.00 NAAA (0.56) NAAANOD1P2RY10GPR34GRIK1
SCHEMBL1514886 0.93 SLC1A2 (0.49) NAAANOD1P2RY10GPR34GRIK1
SCHEMBL476726 0.93 SLC1A2 (0.49) NAAANOD1P2RY10GPR34GRIK1
SCHEMBL27532543 0.93 SLC1A2 (0.49) NAAANOD1P2RY10GPR34GRIK1
SCHEMBL9442151 0.88 NAAA (0.58) NAAANOD1P2RY10GPR34HTR2C
SCHEMBL2983597 0.88 NAAA (0.58) NAAANOD1P2RY10GPR34HTR2C
SCHEMBL2283336 0.88 NAAA (0.58) NAAANOD1P2RY10GPR34HTR2C
SCHEMBL17231345 0.88 NAAA (0.58) NAAANOD1P2RY10GPR34HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140288142-A1 NITRIC OXIDE DONOR COMPOUNDS NICOX SA (FR) 2014-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140288142-A1 NITRIC OXIDE DONOR COMPOUNDS NOS3, NOS2, NOS1 NAAA 2391/4885NOD1 1456/4885P2RY10 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.