Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 7/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.56 |
| ▸ | KDM1A | O60341 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15521729 | 0.82 | ADRA2A (0.75) | ADRA2AADRA2CADRA2BKDM1AGLA | |
| SCHEMBL6822156 | 0.78 | GSK3A (0.56) | SLC2A1GSK3AGSK3BACP1 | |
| SCHEMBL27894556 | 0.74 | KDM4E (0.74) | RECQLHTR3AKMT2AKDM4EMAPT | |
| SCHEMBL20642864 | 0.74 | DNMT1 (0.58) | SLC2A1KMT2AACP1SMARCA2 | |
| SCHEMBL29636698 | 0.73 | ACP1 (0.53) | ADRA2AADRA2CADRA2BSLC2A1KDM4E | |
| SCHEMBL6749969 | 0.72 | SLC2A1 (0.70) | ADRA2AADRA2CADRA2BSLC2A1KDM4E | |
| SCHEMBL7127754 | 0.72 | ADRA2A (1.00) | ADRA2AADRA2CADRA2BKDM1AGLA | |
| SCHEMBL12323601 | 0.72 | KDM4E (0.62) | ADRA2AADRA2CADRA2BKDM1AGLA | |
| SCHEMBL6751610 | 0.71 | SLC2A1 (0.61) | SLC2A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL6748821 | 0.70 | SLC2A1 (0.60) | SLC2A1KDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067513-A1 | ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS | OY JUVANTIA PHARMA LTD (FI) | 2004-08-12 | — | — | WO | claimed |