Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | ACP1 | P24666 | 5/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824920 | 0.78 | ADRA2A (0.56) | GSK3AGSK3BACP1SLC2A1 | |
| SCHEMBL951744 | 0.72 | MAPT (0.65) | GSK3AGSK3B | |
| SCHEMBL802669 | 0.72 | GSK3B (1.00) | GSK3AGSK3BACP1ABCG2ABCB1 | |
| SCHEMBL786208 | 0.72 | GSK3A (0.65) | GSK3AGSK3BACP1ABCG2ABCB1 | |
| SCHEMBL12090776 | 0.71 | ACP1 (0.76) | GSK3AGSK3BACP1ABCG2ABCB1 | |
| SCHEMBL6859623 | 0.71 | ALDH1A1 (0.63) | GSK3AGSK3B | |
| SCHEMBL30946935 | 0.71 | ALDH1A1 (0.63) | GSK3AGSK3B | |
| SCHEMBL30388558 | 0.71 | ALDH1A1 (0.63) | GSK3AGSK3B | |
| SCHEMBL17600557 | 0.71 | ALDH1A1 (0.63) | GSK3AGSK3B | |
| SCHEMBL27986152 | 0.71 | ALDH1A1 (0.63) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067513-A1 | ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS | OY JUVANTIA PHARMA LTD (FI) | 2004-08-12 | — | — | WO | disclosed |