Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.67 |
| ▸ | CETP | P11597 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.57 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13342791 | 0.91 | TDP1 (0.60) | P2RX7TDP1HDAC1HDAC2CETP | |
| SCHEMBL15528617 | 0.90 | ALDH1A1 (0.71) | P2RX7TDP1CETPHPGDALDH1A1 | |
| SCHEMBL12323604 | 0.88 | CETP (0.77) | P2RX7HDAC1HDAC2CETPHDAC3 | |
| SCHEMBL28256535 | 0.88 | CETP (0.77) | P2RX7HDAC1HDAC2CETPHDAC3 | |
| SCHEMBL28258088 | 0.88 | CETP (0.77) | P2RX7HDAC1HDAC2CETPHDAC3 | |
| SCHEMBL16379921 | 0.87 | ALDH1A1 (0.66) | P2RX7HDAC1HDAC2CETPHDAC3 | |
| SCHEMBL13642228 | 0.84 | HDAC1 (0.60) | P2RX7TDP1HDAC1HDAC2CETP | |
| SCHEMBL5923566 | 0.84 | P2RX7 (1.00) | P2RX7TDP1HDAC1HDAC2CETP | |
| SCHEMBL13626624 | 0.84 | HDAC3 (0.56) | P2RX7TDP1HDAC1HDAC2HDAC3 | |
| SCHEMBL5923694 | 0.84 | P2RX7 (1.00) | P2RX7TDP1HDAC1HDAC2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11090273-B2 | Tagged poly(ester amide urethane)s, nanoparticles formed from same, and uses thereof | CORNELL UNIVERSITY (US) | 2021-08-17 | — | — | US | disclosed |
| US-20200129447-A1 | TAGGED POLY(ESTER AMIDE URETHANE)S, NANOPARTICLES FORMED FROM SAME, AND USES THEREOF | CORNELL UNIVERSITY | 2020-04-30 | — | — | US | disclosed |
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |
| EP-1277790-A2 | Nucleators for crystallizable thermoplastic polymers | Ciba SC Holding AG (CH) | 2003-01-22 | — | — | EP | disclosed |
| EP-0940431-A1 | Nucleators for crystallizable thermoplastic polymers | Universität Bayreuth (DE) | 1999-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11090273-B2 | Tagged poly(ester amide urethane)s, nanoparticles formed from same, and uses thereof | UGGT1, PARG, GNE | P2RX7 4508/4885TDP1 1723/4885HDAC1 1589/4885 |
| US-20200129447-A1 | TAGGED POLY(ESTER AMIDE URETHANE)S, NANOPARTICLES FORMED FROM SAME, AND USES THEREOF | UGGT1, PARG, GNE | P2RX7 4508/4885TDP1 1723/4885HDAC1 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.