Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OGT | O15294 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715855 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ATHRBPTGS2 | |
| SCHEMBL6715480 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APTGS2HTT | |
| SCHEMBL6722718 | 0.78 | MEN1 (0.64) | ALDH1A1MEN1KMT2ATHRBHTT | |
| SCHEMBL6715700 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2APTGS2HTT | |
| SCHEMBL8337687 | 0.74 | CTSS (0.57) | ALDH1A1MEN1KMT2ATHRBHTT | |
| SCHEMBL6727017 | 0.72 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2APTGS2HTT | |
| SCHEMBL6715723 | 0.72 | MEN1 (0.55) | ALDH1A1MEN1KMT2ATHRBPTGS2 | |
| SCHEMBL6719402 | 0.71 | TP53 (0.56) | MEN1KMT2ATHRBNLRP3 | |
| SCHEMBL12812272 | 0.70 | POLB (0.65) | ALDH1A1MEN1KMT2APTGS2HTT | |
| SCHEMBL7582497 | 0.70 | HTT (0.49) | ALDH1A1MEN1KMT2APTGS2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |