Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488558 | 0.83 | ALDH1A1 (0.49) | HTTALDH1A1CLCN2LMNAMAPT | |
| SCHEMBL13240829 | 0.83 | ALDH1A1 (0.49) | HTTALDH1A1CLCN2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL2481840 | 0.82 | ALDH1A1 (0.48) | HTTALDH1A1CLCN2LMNAMAPT | |
| SCHEMBL2485161 | 0.79 | MEN1 (0.45) | ALDH1A1MEN1KMT2APTGS2CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL17997772 | 0.78 | MEN1 (0.44) | ALDH1A1MEN1KMT2APTGS2CYP2C19 | |
| SCHEMBL11130746 | 0.77 | HTT (0.60) | HTTALDH1A1MEN1KMT2ACLCN2 | |
| SCHEMBL7574039 | 0.77 | FPR2 (0.47) | ALDH1A1LMNACYP2D6NAALAD2RPS6KB1 | |
| SCHEMBL360635 | 0.76 | CXCL8 (0.45) | ALDH1A1MEN1KMT2APTGS2TSHR | |
| SCHEMBL7576115 | 0.76 | KMT2A (0.46) | ALDH1A1KMT2ALMNACYP2D6NAALAD2 | |
| SCHEMBL7583894 | 0.75 | CRHBP (0.56) | HTTALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |