SCHEMBL6825405

SCHEMBL6825405

CCOC(=O)C(C)(N)C1CCCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
FKBP1A P62942 2/20 0.36
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
MAPT P10636 2/20 0.36
THRB P10828 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALOX15 P16050 1/20 0.35
HPGD P15428 2/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7435757 0.83 ALDH1A1 (0.38) ALDH1A1FKBP1AMAPTTHRBATM
SCHEMBL7439983 0.81 ALDH1A1 (0.40) ALDH1A1MAPTTHRBATML3MBTL1
SCHEMBL10028034 0.81 ALDH1A1 (0.39) ALDH1A1FKBP1ACYP4F2CYP4A11THRB
SCHEMBL28857843 0.80 EPHX1 (0.40) MAPTNPC1TSHRRAB9AHSD17B10
SCHEMBL3115326 0.80 ALDH1A1 (0.37) ALDH1A1CYP4F2CYP4A11THRBALOX15
SCHEMBL16732122 0.79 ALDH1A1 (0.41) ALDH1A1FKBP1ACYP4F2CYP4A11MAPT
SCHEMBL19071938 0.79 ALDH1A1 (0.41) ALDH1A1FKBP1ACYP4F2CYP4A11MAPT
SCHEMBL11477919 0.79 ALDH1A1 (0.38) ALDH1A1FKBP1ACYP4F2CYP4A11MAPT
SCHEMBL28770712 0.79 EPHX1 (0.43) ALDH1A1MAPTKDM4ENPC1TSHR
SCHEMBL7352590 0.79 EPHX1 (0.43) ALDH1A1MAPTKDM4ENPC1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004087643-A1 DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2004-10-14 WO disclosed