Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439983 | 0.98 | ALDH1A1 (0.40) | ALDH1A1ALOX15THRBATML3MBTL1 | |
| SCHEMBL6825405 | 0.83 | ALDH1A1 (0.37) | ALDH1A1ALOX15THRBATML3MBTL1 | |
| SCHEMBL28867351 | 0.80 | ALDH1A1 (0.40) | ALDH1A1THRBATML3MBTL1KMT2A | |
| SCHEMBL7783891 | 0.78 | ALDH1A1 (0.42) | ALDH1A1THRBATML3MBTL1GAA | |
| SCHEMBL11467470 | 0.78 | ALDH1A1 (0.39) | ALDH1A1THRBATML3MBTL1GAA | |
| SCHEMBL10028034 | 0.78 | ALDH1A1 (0.39) | ALDH1A1THRBATML3MBTL1KMT2A | |
| SCHEMBL11477919 | 0.77 | ALDH1A1 (0.38) | ALDH1A1THRBATML3MBTL1GAA | |
| SCHEMBL19071938 | 0.77 | ALDH1A1 (0.41) | ALDH1A1THRBATML3MBTL1GAA | |
| SCHEMBL16732047 | 0.77 | ALDH1A1 (0.38) | ALDH1A1THRBATML3MBTL1KMT2A | |
| SCHEMBL17420411 | 0.77 | ALDH1A1 (0.39) | ALDH1A1THRBATML3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |