SCHEMBL68255

SCHEMBL68255

Oc1cc(Cl)c(Cc2cc(Cl)c(O)cc2Cl)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.57
TSHR P16473 5/20 0.57
HPGD P15428 5/20 0.57
CYP3A4 P08684 7/20 0.50
ALOX15 P16050 4/20 0.50
HIF1A Q16665 4/20 0.50
HSP90AA1 P07900 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ALOX12 P18054 3/20 0.50
USP2 O75604 3/20 0.50
MAPT P10636 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HSPA5 P11021 3/20 0.50
CASP1 P29466 2/20 0.50
LMNA P02545 2/20 0.50
HSPD1 P10809 2/20 0.50
IDO1 P14902 2/20 0.50
HTT P42858 2/20 0.50
BLM P54132 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5385953 0.82 TSHR (0.55) HSD17B10TSHRHPGDCYP3A4ALOX15
SCHEMBL69620 0.81 CYP3A4 (0.58) HSD17B10TSHRHPGDCYP3A4ALOX15
SCHEMBL11711418 0.81 HPGD (0.62) HSD17B10TSHRHPGDCYP3A4ALOX15
SCHEMBL25448692 0.80 HSD17B10 (0.52) HSD17B10TSHRHPGDCYP3A4ALOX15
SCHEMBL10941332 0.80 TSHR (0.52) HSD17B10TSHRHPGDCYP3A4ALOX15
SCHEMBL8350554 0.80 TSHR (0.52) HSD17B10TSHRHPGDCYP3A4ALOX15
SCHEMBL48305 0.80 HSD17B10 (0.86) HSD17B10TSHRHPGDCYP3A4ALOX15
SCHEMBL11273405 0.78 HPGD (0.44) HSD17B10TSHRHPGDCYP3A4ALOX15
SCHEMBL7953262 0.77 AHR (0.42) HSD17B10TSHRHPGDCYP3A4ALOX15
SCHEMBL10940941 0.77 TSHR (0.48) HSD17B10TSHRHPGDCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3965033-A Process for the production of oil-containing microcapsules FUJI PHOTO FILM CO., LTD. (JA) 1976-06-22 US claimed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-3965033-A Process for the production of oil-containing microcapsules FUJI PHOTO FILM CO., LTD. (JA) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 HSD17B10 2777/4885TSHR 3263/4885HPGD 3275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.