SCHEMBL7953262

SCHEMBL7953262

Clc1cc(Cl)c(Cc2cc(Cl)c(Cl)cc2Cl)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.42
MAPK1 P28482 3/20 0.42
HPGD P15428 4/20 0.38
TSHR P16473 3/20 0.38
HSD17B10 Q99714 3/20 0.38
CYP3A4 P08684 4/20 0.37
PTPN5 P54829 5/20 0.35
HSP90AA1 P07900 3/20 0.35
IDO1 P14902 2/20 0.35
MEN1 O00255 2/20 0.35
USP2 O75604 2/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
HSPD1 P10809 2/20 0.35
HSPA5 P11021 2/20 0.35
ALOX15 P16050 2/20 0.35
ALOX12 P18054 2/20 0.35
HTT P42858 2/20 0.35
BLM P54132 2/20 0.35
HSPE1 P61604 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11779597 0.78 AHR (0.40) AHRMAPK1HPGDTSHRHSD17B10
SCHEMBL1807453 0.77 GAA (0.63) MAPK1TSHRHSD17B10CYP3A4ALOX15
SCHEMBL68255 0.77 HSD17B10 (0.57) MAPK1HPGDTSHRHSD17B10CYP3A4
SCHEMBL9396186 0.75 MAPK1 (0.38) AHRMAPK1HPGDTSHRHSD17B10
SCHEMBL11314527 0.75 IDO1 (0.54) AHRMAPK1HPGDTSHRHSD17B10
SCHEMBL11219358 0.75 GRIN2D (0.52) AHRMAPK1HPGDTSHRHSD17B10
SCHEMBL17552704 0.75 MAPK1 (0.38) AHRMAPK1HPGDTSHRHSD17B10
SCHEMBL9567411 0.75 HSD17B10 (0.41) AHRMAPK1HPGDTSHRHSD17B10
SCHEMBL900658 0.75 MAPK1 (0.38) AHRMAPK1HPGDTSHRHSD17B10
SCHEMBL9567410 0.75 MAPK1 (0.38) AHRMAPK1HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265620-B1 REACTING OLEFINIC COMPOUND WITH CARBON MONOXIDE AND HYDROGEN IN PRESENCE OF CATALYST CONTAINING METAL OF GROUP 8 TO 10 AND TRIVALENT ORANIC PHOSPHORUS COMPOUND TO PRODUCE ALDEHYDE MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-24 US disclosed