SCHEMBL8350554

SCHEMBL8350554

Oc1cc(Cl)c(CCCc2cc(Cl)c(O)cc2Cl)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
HSD17B10 Q99714 4/20 0.52
HPGD P15428 3/20 0.52
ALOX15 P16050 3/20 0.42
ALOX12 P18054 2/20 0.42
CYP3A4 P08684 3/20 0.41
ALDH1A1 P00352 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSP90AA1 P07900 2/20 0.37
MEN1 O00255 1/20 0.37
SLC22A1 O15245 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
HSPD1 P10809 1/20 0.37
HSPA5 P11021 1/20 0.37
IDO1 P14902 1/20 0.37
CASP1 P29466 1/20 0.37
HTT P42858 1/20 0.37
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10940941 0.82 TSHR (0.48) TSHRHSD17B10HPGDALOX15ALOX12
SCHEMBL68255 0.80 HSD17B10 (0.57) TSHRHSD17B10HPGDALOX15ALOX12
SCHEMBL5385953 0.78 TSHR (0.55) TSHRHSD17B10HPGDALOX15ALOX12
SCHEMBL2474272 0.77 NPSR1 (0.47) TSHRHSD17B10HPGDCA2
SCHEMBL25448692 0.76 HSD17B10 (0.52) TSHRHSD17B10HPGDALOX15ALOX12
SCHEMBL10941332 0.76 TSHR (0.52) TSHRHSD17B10HPGDALOX15ALOX12
SCHEMBL1569803 0.76 HSD17B10 (0.41) TSHRHSD17B10HPGDALOX15CYP3A4
SCHEMBL48305 0.76 HSD17B10 (0.86) TSHRHSD17B10HPGDALOX15ALOX12
SCHEMBL16736745 0.74 TYR (0.53) TSHRHSD17B10HPGDALOX15ALOX12
SCHEMBL68685 0.74 TYR (0.53) TSHRHSD17B10HPGDALOX15CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994596-A Method for preparing high purity indane bisphenols MOLECULAR OPTOELECTRONICS CORPORATION (US) 1999-11-30 US disclosed