Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823065 | 0.86 | — | — | |
| SCHEMBL6823010 | 0.82 | USP2 (0.44) | GPR119 | |
| SCHEMBL6823567 | 0.76 | USP2 (0.43) | GPR119 | |
| SCHEMBL6822715 | 0.70 | USP2 (0.42) | GPR119 | |
| SCHEMBL6819442 | 0.69 | DDB1 (0.34) | GPR119 | |
| SCHEMBL6823231 | 0.65 | USP2 (0.41) | GPR119 | |
| SCHEMBL371222 | 0.62 | USP2 (0.45) | GPR119 | |
| SCHEMBL28990172 | 0.62 | CYP4F2 (0.49) | — | |
| SCHEMBL21408130 | 0.61 | KDM1A (0.41) | — | |
| SCHEMBL6825314 | 0.61 | USP2 (0.41) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058763-A1 | 4(SPIROPIPERIDINYL)METHYL SUBSTITUTED PYRROLIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2004-07-15 | — | — | WO | disclosed |