SCHEMBL682587

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8212933	0.86	KMT2A (0.48)	KDM4EALDH1A1MEN1KMT2ASMN1; SMN2
	SCHEMBL3929708	0.84	KDM4E (0.42)	USP2KDM4EALDH1A1MAPTKMT2A
	SCHEMBL2512261	0.81	GABRR1 (0.43)	KDM4EALDH1A1MAPTSMN1; SMN2HSD17B10
	SCHEMBL14177816	0.81	TSHR (0.45)	USP2KDM4EALDH1A1MAPTKMT2A
	SCHEMBL1201703	0.80	KDM4E (0.41)	USP2KDM4EALDH1A1MAPTMEN1
	Hydrochloric Acid SCHEMBL1375897	0.79	GABRR1 (0.42)	KDM4EALDH1A1MAPTSMN1; SMN2HSD17B10
	SCHEMBL7676177	0.79	HTT (0.44)	USP2ALDH1A1MAPTSMN1; SMN2GAA
	SCHEMBL7842867	0.79	SMN1; SMN2 (0.34)	USP2SMN1; SMN2
	SCHEMBL3655249	0.79	USP2 (0.35)	USP2KDM4EALDH1A1MAPTMEN1
	SCHEMBL23038543	0.78	USP2 (0.34)	USP2KDM4EALDH1A1GAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.