Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL682587 | 0.86 | USP2 (0.49) | KMT2AMEN1KDM4EALDH1A1TDP1 | |
| SCHEMBL16115753 | 0.83 | MAPK1 (0.49) | KMT2AMEN1KDM4EALDH1A1TDP1 | |
| SCHEMBL10412685 | 0.83 | KMT2A (0.44) | KMT2AMEN1KDM4EALDH1A1TDP1 | |
| SCHEMBL8015267 | 0.82 | KMT2A (0.44) | KMT2AMEN1KDM4EALDH1A1TDP1 | |
| SCHEMBL7826351 | 0.82 | KMT2A (0.44) | KMT2AMEN1KDM4EALDH1A1TDP1 | |
| SCHEMBL2512261 | 0.78 | GABRR1 (0.43) | KDM4EALDH1A1TDP1HSD17B10SMN1; SMN2 | |
| SCHEMBL7676177 | 0.77 | HTT (0.44) | ALDH1A1SMN1; SMN2GAACA2L3MBTL1 | |
| SCHEMBL7842867 | 0.77 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1375897 | 0.77 | GABRR1 (0.42) | KDM4EALDH1A1TDP1HSD17B10SMN1; SMN2 | |
| SCHEMBL30559573 | 0.76 | SMPD1 (0.33) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |