Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993517 | 0.76 | USP2 (0.36) | USP2SMN1; SMN2NR1H2FAAHGPR119 | |
| SCHEMBL3324006 | 0.70 | ALDH1A1 (0.49) | SMN1; SMN2NR1H2GPR119ESR2HPGD | |
| SCHEMBL12610885 | 0.68 | ESR2 (0.40) | USP2SMN1; SMN2ADORA1NR1H2GPR119 | |
| SCHEMBL1515490 | 0.68 | USP2 (0.53) | USP2SMN1; SMN2ADORA1NR1H2GPR119 | |
| SCHEMBL653566 | 0.64 | USP2 (0.58) | USP2SMN1; SMN2NR1H2GPR119HPGD | |
| SCHEMBL17033316 | 0.64 | USP2 (0.38) | USP2SMN1; SMN2ADORA1NR1H2GPR119 | |
| SCHEMBL200712 | 0.64 | USP2 (0.41) | USP2SMN1; SMN2NR1H2GPR119ESR2 | |
| SCHEMBL18294 | 0.64 | USP2 (0.69) | USP2SMN1; SMN2NR1H2GPR119HPGD | |
| SCHEMBL698803 | 0.64 | USP2 (0.69) | USP2SMN1; SMN2NR1H2GPR119HPGD | |
| SCHEMBL29782153 | 0.63 | USP2 (0.40) | USP2SMN1; SMN2ADORA1NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740647-B1 | AMIDINES AND HYDROXYAMIDINE DERIVATIVES | ABBOTT GMBH & CO., KG (DE) | 2004-05-25 | — | — | US | disclosed |