Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30589354 | 0.85 | HDAC1 (0.49) | RAB9AGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL29634427 | 0.84 | HTT (0.63) | RAB9AGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL29634479 | 0.82 | HTT (0.66) | RAB9AMAPTSMN1; SMN2NPC1TSHR | |
| SCHEMBL29173061 | 0.82 | HDAC1 (0.49) | RAB9AGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL28138491 | 0.82 | HTT (0.65) | GAAMAPTSMN1; SMN2ALDH1A1HDAC6 | |
| SCHEMBL4538968 | 0.80 | ALDH1A1 (0.56) | RAB9AGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL29634403 | 0.80 | SMN1; SMN2 (0.62) | RAB9AGAAMAPTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL18281395 | 0.79 | ALDH1A1 (0.54) | RAB9AGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL28715490 | 0.78 | SMN1; SMN2 (0.51) | RAB9AGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL13073616 | 0.78 | ACHE (0.67) | RAB9AGAAMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |