Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209152 | 0.90 | SLC6A4 (0.51) | SLC6A4SLC6A9TBXAS1ALDH1A1 | |
| SCHEMBL6826714 | 0.86 | SLC6A9 (0.48) | SLC6A4SLC6A9TBXAS1ALDH1A1 | |
| SCHEMBL6826141 | 0.86 | SLC6A4 (0.51) | SLC6A4SLC6A9ALDH1A1 | |
| SCHEMBL6828473 | 0.86 | SLC6A4 (0.43) | SLC6A4SLC6A9 | |
| SCHEMBL6826663 | 0.85 | MTNR1B (0.45) | SLC6A4SLC6A9 | |
| SCHEMBL6566281 | 0.79 | SLC6A4 (0.55) | SLC6A4SLC6A9 | |
| SCHEMBL6826316 | 0.78 | SLC6A9 (0.68) | SLC6A9ALDH1A1 | |
| SCHEMBL6566442 | 0.76 | FNTA (0.47) | SLC6A4SLC6A9 | |
| SCHEMBL6258432 | 0.75 | SLC6A4 (0.50) | SLC6A4SLC6A9ALDH1A1 | |
| SCHEMBL6566262 | 0.75 | SLC6A9 (0.49) | SLC6A4SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294677-B1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | PFIZER PROD INC (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1294677-A1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | Pfizer Products Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000602-A1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | PFIZER PRODUCTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |