Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2627831 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL1759453 | 0.79 | CCNE2 (0.36) | KDM4EALDH1A1GAACCNE2CDK4 | |
| SCHEMBL23704951 | 0.77 | SMN1; SMN2 (0.37) | KDM4EALDH1A1GAACYP1A2LMNA | |
| SCHEMBL29868118 | 0.77 | SMN1; SMN2 (0.37) | KDM4EALDH1A1GAACYP1A2LMNA | |
| SCHEMBL17542095 | 0.75 | TDP1 (0.60) | KDM4EALDH1A1CYP1A2LMNATDP1 | |
| SCHEMBL6826490 | 0.74 | LMNA (0.35) | GAACYP1A2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL26699075 | 0.74 | PDE4A (0.36) | KDM4EALDH1A1GAACYP1A2LMNA | |
| SCHEMBL10889888 | 0.74 | HSP90AA1 (0.39) | KDM4ECCNE2CDK4CCND1CCNE1 | |
| SCHEMBL18978202 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1GAACYP1A2LMNA | |
| SCHEMBL3109540 | 0.73 | ALDH1A1 (0.42) | KDM4EALDH1A1CYP1A2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111000-A2 | PIPERIDYL DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2004-12-23 | — | — | WO | disclosed |