Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | EDNRB | P24530 | 5/20 | 0.33 |
| ▸ | EDNRA | P25101 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12757466 | 0.77 | LMNA (0.47) | LMNASMN1; SMN2L3MBTL1EDNRBEDNRA | |
| SCHEMBL12701526 | 0.77 | PDE2A (0.48) | LMNASMN1; SMN2L3MBTL1EDNRBEDNRA | |
| SCHEMBL5321210 | 0.76 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2L3MBTL1EDNRBEDNRA | |
| SCHEMBL25083887 | 0.75 | TLR7 (0.40) | SMN1; SMN2GAAKRASSOS1L3MBTL1 | |
| SCHEMBL6826481 | 0.74 | KDM4E (0.36) | LMNASMN1; SMN2GAAL3MBTL1CYP1A2 | |
| SCHEMBL23704951 | 0.74 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2GAAL3MBTL1CYP1A2 | |
| SCHEMBL29868118 | 0.74 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2GAAL3MBTL1CYP1A2 | |
| SCHEMBL6826219 | 0.73 | SMN1; SMN2 (0.36) | LMNASMN1; SMN2L3MBTL1EDNRBEDNRA | |
| SCHEMBL6335452 | 0.72 | L3MBTL1 (0.48) | LMNASMN1; SMN2L3MBTL1EDNRBEDNRA | |
| SCHEMBL26699075 | 0.71 | PDE4A (0.36) | LMNAGAAL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111000-A2 | PIPERIDYL DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2004-12-23 | — | — | WO | disclosed |