Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 2/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827986 | 0.82 | RAB9A (0.51) | HTTPBRM1CYP19A1MAOBRAB9A | |
| SCHEMBL6828122 | 0.82 | PBRM1 (0.61) | ARPBRM1CYP19A1MAOBCYP3A4 | |
| SCHEMBL6828002 | 0.78 | ABCB1 (0.60) | ARALDH1A1MAPTHTTCYP19A1 | |
| SCHEMBL6825975 | 0.78 | MAOB (0.56) | ARMAPTCYP19A1MAOBCYP3A4 | |
| SCHEMBL68075 | 0.76 | PBRM1 (0.67) | ARALDH1A1MAPTPKMHPGD | |
| SCHEMBL10536102 | 0.74 | AR (0.63) | ARALDH1A1MAPTPKMHPGD | |
| SCHEMBL22624375 | 0.73 | AR (0.54) | ARALDH1A1MAPTPKMHPGD | |
| SCHEMBL22616365 | 0.73 | AR (0.54) | ARALDH1A1MAPTPKMHPGD | |
| SCHEMBL22624453 | 0.73 | AR (0.54) | ARALDH1A1MAPTPKMHPGD | |
| SCHEMBL22617371 | 0.73 | AR (0.54) | ARALDH1A1MAPTPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113317-A1 | NOVEL ANTIMICROBIAL CHROMAN-4-ONES | ERNST-MORITZ-ARNDT- UNIVERSITÄT (DE) | 2004-12-29 | — | — | WO | claimed |
| WO-2004113317-A1 | NOVEL ANTIMICROBIAL CHROMAN-4-ONES | ERNST-MORITZ-ARNDT- UNIVERSITÄT (DE) | 2004-12-29 | — | — | WO | disclosed |