Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827986 | 0.81 | RAB9A (0.51) | KDM4ENPC1RAB9ACYP19A1MAOB | |
| SCHEMBL12264771 | 0.80 | ABCB1 (0.66) | ABCB1ARABCG2KDM4ENPC1 | |
| SCHEMBL11381876 | 0.80 | ABCB1 (0.66) | ABCB1ARABCG2KDM4ENPC1 | |
| SCHEMBL6828122 | 0.78 | PBRM1 (0.61) | ABCB1ARABCG2RAB9ACYP19A1 | |
| SCHEMBL29222646 | 0.78 | ABCB1 (0.64) | ABCB1ARABCG2KDM4ENPC1 | |
| SCHEMBL6826536 | 0.78 | AR (0.51) | ABCB1ARABCG2RAB9AALDH1A1 | |
| SCHEMBL28118581 | 0.78 | ABCB1 (0.64) | ABCB1ARABCG2KDM4ENPC1 | |
| SCHEMBL22680315 | 0.76 | ABCB1 (0.87) | ABCB1ARABCG2KDM4ENPC1 | |
| SCHEMBL4394832 | 0.75 | AR (1.00) | ABCB1ARABCG2KDM4ENPC1 | |
| SCHEMBL126192 | 0.75 | AR (1.00) | ABCB1ARABCG2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113317-A1 | NOVEL ANTIMICROBIAL CHROMAN-4-ONES | ERNST-MORITZ-ARNDT- UNIVERSITÄT (DE) | 2004-12-29 | — | — | WO | claimed |
| WO-2004113317-A1 | NOVEL ANTIMICROBIAL CHROMAN-4-ONES | ERNST-MORITZ-ARNDT- UNIVERSITÄT (DE) | 2004-12-29 | — | — | WO | disclosed |