SCHEMBL6826563

SCHEMBL6826563

NCCOC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 6/20 0.68
NT5E P21589 1/20 0.68
GSK3A P49840 2/20 0.64
RPS6KA3 P51812 2/20 0.64
MAPK14 Q16539 2/20 0.64
TGM2 P21980 1/20 0.63
PNP P00491 1/20 0.61
KRAS P01116 9/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7098413 0.91 HINT1 (0.67) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL6239924 0.91 HINT1 (0.73) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL2533738 0.90 HINT1 (0.69) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL6889003 0.90 HINT1 (0.70) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL2335177 0.89 HINT1 (0.69) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL1138984 0.89 HINT1 (0.75) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL6245258 0.89 HINT1 (0.69) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL5501200 0.89 HINT1 (0.69) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL3925834 0.89 HINT1 (0.64) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL1424945 0.88 HINT1 (0.68) HINT1NT5EGSK3ARPS6KA3MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3454895-B1 INORGANIC POLYATOMIC OXYANIONS FOR PROTECTING AGAINST ANTIGENIC DAMAGE DURING PATHOGEN INACTIVATION FOR VACCINE PRODUCTION NAJIT TECH INC (US) 2024-03-27 EP disclosed
US-11844832-B2 Inorganic polyatomic oxyanions for protecting against antigenic damage during pathogen inactivation for vaccine production NAJIT TECHNOLOGIES, INC. (US) 2023-12-19 US disclosed
US-20210196812-A1 INORGANIC POLYATOMIC OXYANIONS FOR PROTECTING AGAINST ANTIGENIC DAMAGE DURING PATHOGEN INACTIVATION FOR VACCINE PRODUCTION Najít Technologies, Inc. 2021-07-01 US disclosed
US-10744198-B2 Inorganic polyatomic oxyanions for protecting against antigenic damage during pathogen inactivation for vaccine production NAJIT TECHNOLOGIES, INC. (US) 2020-08-18 US disclosed
CN-110199023-A Ahlport syndrome medicine 第一三共株式会社 2019-09-03 CN disclosed
US-20190201520-A1 INORGANIC POLYATOMIC OXYANIONS FOR PROTECTING AGAINST ANTIGENIC DAMAGE DURING PATHOGEN INACTIVATION FOR VACCINE PRODUCTION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-07-04 US disclosed
EP-3454895-A1 INORGANIC POLYATOMIC OXYANIONS FOR PROTECTING AGAINST ANTIGENIC DAMAGE DURING PATHOGEN INACTIVATION FOR VACCINE PRODUCTION Najit Technologies, Inc. (US) 2019-03-20 EP disclosed
WO-2017197034-A1 INORGANIC POLYATOMIC OXYANIONS FOR PROTECTING AGAINST ANTIGENIC DAMAGE DURING PATHOGEN INACTIVATION FOR VACCINE PRODUCTION NAJIT TECHNOLOGIES, INC. (US) 2017-11-16 WO disclosed
US-20040214198-A1 Allele-targeted RNA interference UNIVERSITY OF MASSACHUSETTS 2004-10-28 US disclosed
WO-2004046324-A2 ALLELE-TARGETED RNA INTERFERENCE UNIVERSITY OF MASSACHUSETTS (US) 2004-06-03 WO disclosed
EP-0977832-A4 METHOD FOR INACTIVATING A VIRUS VI TECHNOLOGIES INC (US) 2001-09-05 EP disclosed
US-6252048-B1 FUSION PROTEIN FOR THE TREATMENT AND PREVENTION OF CANCER ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE 2001-06-26 US disclosed
EP-0977832-A1 METHOD FOR INACTIVATING A VIRUS Pentose Pharmaceuticals, Inc. (US) 2000-02-09 EP disclosed
US-5891705-A Method for inactivating a virus PENTOSE PHARMACEUTICALS, INC. (US) 1999-04-06 US disclosed
WO-1998045415-A1 METHOD FOR INACTIVATING A VIRUS PENTOSE PHARMACEUTICALS, INC. (US) 1998-10-15 WO disclosed
WO-1998017684-A2 DNA SEQUENCES ENCODING FUSIONS OF DNA REPAIR PROTEINS AND USES THEREOF ADVANCED RESEARCH & TECHNOLOGY INSTITUTE (US) 1998-04-30 WO disclosed
US-5622945-A Rubyrin macrocycles BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1997-04-22 US disclosed
WO-1996021665-A1 TURCASARINS, NOVEL EXPANDED PORPHYRINS, AND USES THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1996-07-18 WO disclosed
US-5410045-A As anion chelators, receptors and transporters BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210196812-A1 INORGANIC POLYATOMIC OXYANIONS FOR PROTECTING AGAINST ANTIGENIC DAMAGE DURING PATHOGEN INACTIVATION FOR VACCINE PRODUCTION OGG1, EIF2AK2, AS3MT HINT1 2419/4885NT5E 2675/4885GSK3A 3510/4885
US-20190201520-A1 INORGANIC POLYATOMIC OXYANIONS FOR PROTECTING AGAINST ANTIGENIC DAMAGE DURING PATHOGEN INACTIVATION FOR VACCINE PRODUCTION OGG1, EIF2AK2, AS3MT HINT1 2457/4885NT5E 2696/4885GSK3A 3574/4885
US-11844832-B2 Inorganic polyatomic oxyanions for protecting against antigenic damage during pathogen inactivation for vaccine production OGG1, EIF2AK2, AS3MT HINT1 2419/4885NT5E 2675/4885GSK3A 3510/4885
US-10744198-B2 Inorganic polyatomic oxyanions for protecting against antigenic damage during pathogen inactivation for vaccine production OGG1, EIF2AK2, AS3MT HINT1 2457/4885NT5E 2696/4885GSK3A 3574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.