SCHEMBL1138984

SCHEMBL1138984

CCOC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.75

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 6/20 0.75
NT5E P21589 1/20 0.69
ADORA3 P0DMS8 1/20 0.66
GSK3A P49840 2/20 0.65
RPS6KA3 P51812 2/20 0.65
MAPK14 Q16539 2/20 0.65
TGM2 P21980 1/20 0.64
PNP P00491 1/20 0.62
FUT5 Q11128 1/20 0.59
IMPDH2 P12268 1/20 0.58
IMPDH1 P20839 1/20 0.58
KRAS P01116 5/20 0.58
HPGD P15428 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6239924 0.92 HINT1 (0.73) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL18520144 0.91 HINT1 (0.64) HINT1NT5EADORA3GSK3ARPS6KA3
SCHEMBL6889003 0.91 HINT1 (0.70) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL2335177 0.90 HINT1 (0.69) HINT1NT5EGSK3ARPS6KA3MAPK14
2'-Beta-Methyl-Guanosine SCHEMBL11965261 0.90 HINT1 (0.75) HINT1NT5EADORA3GSK3ARPS6KA3
2'-Beta-Methyl-Guanosine SCHEMBL14178410 0.90 HINT1 (0.75) HINT1NT5EADORA3GSK3ARPS6KA3
2'-Beta-Methyl-Guanosine SCHEMBL15338533 0.90 HINT1 (0.75) HINT1NT5EADORA3GSK3ARPS6KA3
2'-Beta-Methyl-Guanosine SCHEMBL383785 0.90 HINT1 (0.75) HINT1NT5EADORA3GSK3ARPS6KA3
2'-Beta-Methyl-Guanosine SCHEMBL116165 0.90 HINT1 (0.75) HINT1NT5EADORA3GSK3ARPS6KA3
SCHEMBL10520858 0.90 HINT1 (0.69) HINT1NT5EGSK3ARPS6KA3MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
US-12357664-B2 Optimized oncolytic viruses and uses thereof SATOR THERAPEUTICS (US) 2025-07-15 US claimed
WO-2025038853-A1 USHER SYNDROME-RELATED GENE MODIFICATION AMBER BIO INC. (US) 2025-02-20 WO claimed
WO-2024229296-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-11-07 WO claimed
EP-4244356-A1 CHEMICAL MODIFICATIONS FOR INHIBITING EXPRESSION OF ALDH2 Dicerna Pharmaceuticals, Inc. (US) 2023-09-20 EP claimed
WO-2022104366-A1 CHEMICAL MODIFICATIONS FOR INHIBITING EXPRESSION OF ALDH2 DICERNA PHARMACEUTICALS, INC. (US) 2022-05-19 WO claimed
US-20220088097-A1 OPTIMIZED ONCOLYTIC VIRUSES AND USES THEREOF SATOR THERAPEUTICS 2022-03-24 US claimed
EP-0948256-A4 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA UNIV WASHINGTON (US) 2007-10-24 EP claimed
US-6887707-B2 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA UNIVERSITY OF WASHINGTON (US) 2005-05-03 US claimed
US-20030119764-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2003-06-26 US claimed
EP-0948256-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1999-10-13 EP claimed
WO-1998018324-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1998-05-07 WO claimed
WO-2026102473-A1 TEMPERATURE DEPENDENT PROBES FOR TARGET DETECTION SPEEDX PTY LTD (AU) 2026-05-21 WO disclosed
WO-2026104647-A1 VACCINE ASTRAZENECA AB (SE) 2026-05-21 WO disclosed
EP-4739794-A1 METHODS, COMPOSITONS, AND SYSTEMS FOR ANALYTE DETECTION Stellaromics, Inc. (US) 2026-05-13 EP disclosed
EP-4735035-A2 SARS-COV-2 RNA VACCINES AND USES THEREOF Seqirus Inc. (US) 2026-05-06 EP disclosed
US-20030119764-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2003-06-26 US disclosed
WO-2003039450-A2 IMPROVEMENTS IN OR RELATING TO INHIBITION OF VIRUSES MEDICAL RESEARCH COUNCIL (GB) 2003-05-15 WO disclosed
EP-0948256-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1999-10-13 EP disclosed
WO-1998018324-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1998-05-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030119764-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA SAMHD1, BCDIN3D, DCTD HINT1 280/4885NT5E 846/4885ADORA3 1762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.