Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 17/20 | 0.63 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826278 | 0.92 | UTS2R (0.53) | SLC6A9UTS2RALDH1A1CYP2D6MAPT | |
| SCHEMBL6826792 | 0.91 | SLC6A9 (0.66) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL7208059 | 0.87 | SLC6A9 (0.74) | SLC6A9UTS2RALDH1A1CYP2D6MAPT | |
| SCHEMBL7213068 | 0.86 | SLC6A9 (0.64) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826614 | 0.85 | SLC6A9 (0.82) | SLC6A9UTS2RALDH1A1CYP2D6MAPT | |
| SCHEMBL6826660 | 0.85 | SLC6A9 (0.82) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826318 | 0.84 | SLC6A9 (0.61) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826941 | 0.83 | SLC6A9 (0.69) | SLC6A9UTS2RALDH1A1CYP2D6MAPT | |
| SCHEMBL6826227 | 0.83 | SLC6A9 (0.60) | SLC6A9UTS2RALDH1A1CYP2D6MAPT | |
| SCHEMBL6823003 | 0.82 | SLC6A9 (0.64) | SLC6A9UTS2RALDH1A1CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294677-B1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | PFIZER PROD INC (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1294677-A1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | Pfizer Products Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| US-6506780-B2 | Benzophenones and sulfones as inhibitors of glycine uptake | PFIZER INC. | 2003-01-14 | — | — | US | disclosed |
| US-20020052401-A1 | Benzophenones and sulfones as inhibitors of glycine uptake | PFIZER INC. | 2002-05-02 | — | — | US | disclosed |
| WO-2002000602-A1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | PFIZER PRODUCTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052401-A1 | Benzophenones and sulfones as inhibitors of glycine uptake | SLC6A1, SLC6A5, SLC1A2 | SLC6A9 9/4885UTS2R 1612/4885ALDH1A1 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.