Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684212 | 0.87 | POLB (0.48) | NPC1MAPTHTTLMNAMEN1 | |
| SCHEMBL7427855 | 0.81 | ALDH1A1 (0.36) | NPC1MAPTHTTLMNAKMT2A | |
| SCHEMBL682698 | 0.80 | GAA (0.38) | NPC1MAPTHTTLMNAMEN1 | |
| SCHEMBL6822071 | 0.79 | EGFR (0.46) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL683508 | 0.78 | ALDH1A1 (0.39) | MAPTHTTMEN1KMT2ANPSR1 | |
| SCHEMBL22147873 | 0.75 | ALDH1A1 (0.42) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL17323234 | 0.72 | LCK (0.46) | NPC1MAPTHPGDPKMRAB9A | |
| SCHEMBL682721 | 0.71 | MEN1 (0.59) | NPC1MAPTHTTMEN1KMT2A | |
| SCHEMBL5848990 | 0.71 | ALDH1A1 (0.51) | NPC1MAPTMEN1KMT2AHPGD | |
| SCHEMBL20620683 | 0.69 | HPGD (0.42) | MAPTHTTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| EP-0368343-B1 | AMELIORATING COMPOSITION FOR DYSMNESIA | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4990516-A | Pyrazolo (1,5-a)pyridine derivatives | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0368343-A2 | Ameliorating composition for dysmnesia | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1990-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | NPC1 2460/4885MAPT 1368/4885HTT 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.