Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 4/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510832 | 0.77 | HTR6 (0.68) | HTR6HTTPKMPOLBCYP3A4 | |
| SCHEMBL29617199 | 0.77 | HTR6 (0.68) | HTR6HTTPKMPOLBCYP3A4 | |
| Hydroxyamine SCHEMBL14672692 | 0.74 | HTR6 (0.65) | HTR6HTTPKMPOLBCYP3A4 | |
| SCHEMBL8386471 | 0.72 | PRKCI (0.55) | HTR6HTTPOLBMAPTPRKCI | |
| SCHEMBL28691440 | 0.72 | PRKCI (0.46) | HTR6HTTPOLBALDH1A1TSHR | |
| SCHEMBL482811 | 0.71 | HTR6 (0.60) | HTR6HTTPKMPOLBMAPT | |
| SCHEMBL6236314 | 0.71 | HTR6 (0.52) | HTR6HTTPOLBALDH1A1TSHR | |
| SCHEMBL28685370 | 0.71 | HTR6 (0.56) | HTR6HTTPKMPOLBALDH1A1 | |
| SCHEMBL3621300 | 0.69 | HTT (0.49) | HTR6HTTPKMPOLBMAPT | |
| SCHEMBL6632663 | 0.67 | HTR6 (0.56) | HTR6HTTPKMPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |