Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827816 | 0.75 | HTT (0.43) | HTTFGFR1PIK3C3MKNK1MKNK2 | |
| SCHEMBL6827332 | 0.73 | NPC1 (0.44) | — | |
| SCHEMBL13052913 | 0.71 | HTT (0.77) | HTTFGFR1 | |
| SCHEMBL6922673 | 0.69 | NR2E1 (0.36) | — | |
| SCHEMBL6827915 | 0.69 | CYP11B1 (0.41) | PDE3BPDE3ALMNATSHR | |
| SCHEMBL6924372 | 0.69 | LMNA (0.41) | HRH3LMNA | |
| SCHEMBL6924757 | 0.68 | P4HTM (0.34) | MKNK1MKNK2 | |
| SCHEMBL6823986 | 0.68 | PDE3B (0.34) | PDE3BMKNK2 | |
| SCHEMBL26709222 | 0.67 | FGFR1 (0.43) | HTTFGFR1PIK3C3PDE2APDE3B | |
| SCHEMBL23266914 | 0.67 | HTT (0.69) | HTTFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |