Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.32 |
| ▸ | STS | P08842 | 4/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922673 | 0.82 | NR2E1 (0.36) | CYP1B1 | |
| SCHEMBL6823986 | 0.81 | PDE3B (0.34) | CYP1B1GRM5MKNK2 | |
| SCHEMBL6827332 | 0.79 | NPC1 (0.44) | CYP1B1 | |
| SCHEMBL6920247 | 0.76 | MKNK1 (0.31) | P4HTMMKNK1MKNK2 | |
| SCHEMBL6827915 | 0.74 | CYP11B1 (0.41) | — | |
| SCHEMBL6922731 | 0.74 | NOTUM (0.49) | GRM5 | |
| SCHEMBL7154816 | 0.69 | SYK (0.35) | GRM5 | |
| SCHEMBL6827232 | 0.68 | HTT (0.44) | MKNK1MKNK2 | |
| SCHEMBL6924372 | 0.67 | LMNA (0.41) | CYP1B1 | |
| SCHEMBL6917984 | 0.67 | NOTUM (0.39) | CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |