Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.36 |
| ▸ | KAT7 | O95251 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917984 | 0.81 | NOTUM (0.39) | HCRTR1HCRTR2KAT7CYP1B1NOTUM | |
| SCHEMBL6827915 | 0.76 | CYP11B1 (0.41) | LMNAKDM4EALDH1A1MAPK1 | |
| SCHEMBL6923841 | 0.72 | KAT7 (0.35) | LMNARAB9AHCRTR1HCRTR2KAT7 | |
| SCHEMBL7425143 | 0.69 | NOTUM (0.51) | KDM4EALDH1A1MAPK1NOTUMHRH3 | |
| SCHEMBL6827232 | 0.69 | HTT (0.44) | LMNAHRH3 | |
| SCHEMBL6922673 | 0.68 | NR2E1 (0.36) | CYP1B1USP30 | |
| SCHEMBL6827665 | 0.68 | CYP1B1 (0.41) | CYP1B1NOTUMGAAMAPTKMT2A | |
| SCHEMBL6827332 | 0.68 | NPC1 (0.44) | RAB9ACYP1B1 | |
| SCHEMBL6823986 | 0.67 | PDE3B (0.34) | CYP1B1 | |
| SCHEMBL6924757 | 0.67 | P4HTM (0.34) | CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |