SCHEMBL6827271

SCHEMBL6827271

Cc1c(N)cc(C)c2c1c1ccccc1n2C(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 3/20 0.50
PRKD3 O94806 1/20 0.39
PRKCG P05129 1/20 0.39
PRKCB P05771 1/20 0.39
PRKCA P17252 1/20 0.39
PRKCH P24723 1/20 0.39
PRKCI P41743 1/20 0.39
PRKCE Q02156 1/20 0.39
PRKCQ Q04759 1/20 0.39
PRKCZ Q05513 1/20 0.39
PRKCD Q05655 1/20 0.39
PRKD1 Q15139 1/20 0.39
CDC25A P30304 1/20 0.39
CDC25C P30307 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6828981 0.85 NPY5R (0.40) NPY5RPRKD3PRKCGPRKCBPRKCA
SCHEMBL6826802 0.82 DHFR (0.40) NPY5RMAPTKDM4EDHFRSLC2A1
SCHEMBL22336448 0.78 MAPT (0.61) NPY5RPRKD3PRKCGPRKCBPRKCA
SCHEMBL6823801 0.77 NPY5R (0.47) NPY5RPRKD3PRKCGPRKCBPRKCA
SCHEMBL1149724 0.77 KDM4E (0.48) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL6826776 0.75 NPY5R (0.49) NPY5RPRKD3PRKCGPRKCBPRKCA
SCHEMBL22336452 0.73 MEN1 (0.44) NPY5RPRKD3PRKCGPRKCBPRKCA
SCHEMBL20097152 0.73 ALKBH5 (0.59) NPY5RPRKD3PRKCGPRKCBPRKCA
SCHEMBL23072091 0.71 BCHE (0.43) NPY5RPRKD3PRKCGPRKCBPRKCA
SCHEMBL20209690 0.71 BCHE (0.43) NPY5RPRKD3PRKCGPRKCBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1531527-A Carbazole derivatives and their use as neuropeptide Y5 receptor ligands 2004-09-22 CN disclosed
US-20040067999-A1 Carbazole derivatives and their use as neuropeptide y5 receptor ligands ASTRAZENECA AB (SE) 2004-04-08 US disclosed
EP-1358157-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS AstraZeneca AB (SE) 2003-11-05 EP disclosed
WO-2002051806-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS ASTRAZENECA AB (SE) 2002-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040067999-A1 Carbazole derivatives and their use as neuropeptide y5 receptor ligands NPY5R, NPY1R, NPY2R NPY5R 1/4885PRKD3 789/4885PRKCG 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.