Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ADH5 | P11766 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824827 | 1.00 | PGR (0.38) | PGRCYP11B1CYP11B2ADH5HTR2A | |
| SCHEMBL6827087 | 0.99 | PGR (0.39) | PGRCYP11B1CYP11B2ADH5HTR2A | |
| SCHEMBL6924518 | 0.89 | PGR (0.36) | PGRCYP11B1CYP11B2ADH5HTR2A | |
| SCHEMBL6827401 | 0.87 | HTR2A (0.39) | CYP11B1CYP11B2HTR2AHTR2CHTR2B | |
| SCHEMBL6827314 | 0.84 | HTR2A (0.44) | CYP11B1CYP11B2ADH5HTR2AHTR2C | |
| SCHEMBL6827985 | 0.82 | CD38 (0.38) | PGRCYP11B1CYP11B2HTR2AHTR2C | |
| SCHEMBL6827215 | 0.77 | NR1I2 (0.38) | CD38LMNACYP3A4NR1I2KDM4B | |
| SCHEMBL6827225 | 0.77 | CD38 (0.43) | HTR2AHTR2CHTR2BCD38LMNA | |
| SCHEMBL6827260 | 0.76 | NOTUM (0.38) | LMNAKAT5NR1I2KDM4BCHRM1 | |
| SCHEMBL6827158 | 0.76 | KDM4E (0.34) | LMNANR1I2KDM4BCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |