Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 12/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827087 | 0.83 | PGR (0.39) | CD38CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL6827401 | 0.82 | HTR2A (0.39) | CD38CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL6827359 | 0.82 | PGR (0.38) | CD38CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL6824827 | 0.82 | PGR (0.38) | CD38CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL6827314 | 0.80 | HTR2A (0.44) | CD38CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL6924518 | 0.73 | PGR (0.36) | CD38CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL6827225 | 0.64 | CD38 (0.43) | CD38HTR2AHTR2CHTR2B | |
| SCHEMBL6827215 | 0.61 | NR1I2 (0.38) | CD38 | |
| SCHEMBL30910359 | 0.60 | CD38 (0.47) | CD38CYP11B1CYP11B2PGR | |
| SCHEMBL7131529 | 0.60 | MLLT3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |