Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CD38 | P28907 | 6/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | ADH5 | P11766 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827401 | 0.87 | HTR2A (0.39) | HTR2AHTR2CHTR2BCD38CYP11B1 | |
| SCHEMBL6827087 | 0.85 | PGR (0.39) | HTR2AHTR2CHTR2BCD38ADH5 | |
| SCHEMBL6827359 | 0.84 | PGR (0.38) | HTR2AHTR2CHTR2BCD38ADH5 | |
| SCHEMBL6827985 | 0.80 | CD38 (0.38) | HTR2AHTR2CHTR2BCD38CYP11B1 | |
| SCHEMBL6924518 | 0.75 | PGR (0.36) | HTR2AHTR2CHTR2BCD38ADH5 | |
| SCHEMBL6827225 | 0.68 | CD38 (0.43) | HTR2AHTR2CHTR2BCD38 | |
| SCHEMBL7131529 | 0.66 | MLLT3 (0.40) | CYP3A4 | |
| SCHEMBL6919056 | 0.63 | MLLT3 (0.44) | CYP3A4 | |
| SCHEMBL12970841 | 0.63 | ALDH1A1 (0.58) | HTR2AHTR2CHTR2BADH5CYP3A4 | |
| SCHEMBL12970842 | 0.63 | ALDH1A1 (0.58) | HTR2AHTR2CHTR2BADH5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |