Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827426 | 0.81 | MAPT (0.55) | ALDH1A1HPGDCYP3A4TSHRCYP2C19 | |
| SCHEMBL8109864 | 0.80 | ATM (0.54) | ALDH1A1HPGDCYP3A4TSHRCYP2C19 | |
| SCHEMBL1008973 | 0.78 | MEN1 (0.60) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL8105644 | 0.77 | MAPKAPK2 (0.46) | ALDH1A1HPGDCYP3A4TSHRCYP2C19 | |
| SCHEMBL8107451 | 0.77 | MAOB (0.49) | ALDH1A1HPGDCYP3A4CYP2C19MAPT | |
| SCHEMBL7654419 | 0.76 | CYP1B1 (0.61) | ALDH1A1HPGDCYP3A4KDM4EHSD17B10 | |
| SCHEMBL6827363 | 0.76 | KDM4E (0.58) | ALDH1A1HPGDCYP3A4TSHRCYP2C19 | |
| SCHEMBL4626639 | 0.76 | CYP3A4 (1.00) | ALDH1A1HPGDCYP3A4TSHRCYP2C19 | |
| SCHEMBL4650574 | 0.76 | HPGD (0.81) | ALDH1A1HPGDCYP3A4TSHRCYP2C19 | |
| SCHEMBL31675843 | 0.76 | CYP3A4 (1.00) | ALDH1A1HPGDCYP3A4TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |