SCHEMBL8109864

SCHEMBL8109864

Cc1ccccc1-c1cc(O)cc(=O)o1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.54
ELAVL1 Q15717 1/20 0.50
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
CYP3A4 P08684 4/20 0.48
GLA P06280 2/20 0.48
ALDH1A1 P00352 6/20 0.44
HPGD P15428 6/20 0.44
HSD17B10 Q99714 4/20 0.44
KDM4E B2RXH2 3/20 0.44
TP53 P04637 2/20 0.44
GAA P10253 2/20 0.44
SLC9A1 P19634 2/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 2/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KCNA3 P22001 2/20 0.41
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1008973 0.81 MEN1 (0.60) ATMMEN1KMT2AALDH1A1HPGD
SCHEMBL6827384 0.80 ALDH1A1 (0.60) MEN1KMT2ACYP3A4GLAALDH1A1
SCHEMBL8105644 0.80 MAPKAPK2 (0.46) ATMELAVL1MEN1KMT2ACYP3A4
SCHEMBL8107451 0.79 MAOB (0.49) ATMELAVL1MEN1KMT2ACYP3A4
SCHEMBL6172775 0.74 SMN1; SMN2 (0.54) MEN1KMT2ACYP3A4GLAALDH1A1
SCHEMBL30228405 0.73 CA9 (0.56) ATMCYP3A4GLAALDH1A1HPGD
SCHEMBL17114051 0.72 HPGD (0.48) ATMMEN1KMT2ACYP3A4ALDH1A1
SCHEMBL7583434 0.72 HPGD (0.70) ATMMEN1KMT2ACYP3A4GLA
SCHEMBL8107735 0.71 CSNK2A2 (0.54) ELAVL1MEN1KMT2ACYP3A4GLA
SCHEMBL8116989 0.71 QPCT (0.59) ELAVL1MEN1KMT2ACYP3A4GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114546-A Aminomethylene derivatives and ultraviolet absorbent comprising thereof CHEMIPRO KASEI KAISHA, LIMITED (JP) 2000-09-05 US disclosed
CN-1236357-A Aminomethylene derivatives and ultraviolet absorber comprising the same CHEMIPRO KASEI KAISHA LTD (JP) 1999-11-24 CN disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed