Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | AR | P10275 | 1/20 | 0.74 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.65 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.65 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.65 |
| ▸ | FYN | P06241 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31675843 | 1.00 | CYP3A4 (1.00) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL4650574 | 0.90 | HPGD (0.81) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL30660103 | 0.85 | AR (1.00) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL5580084 | 0.85 | ALDH1A1 (0.74) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL4443406 | 0.85 | AR (1.00) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL253522 | 0.85 | HPGD (0.78) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL17786446 | 0.84 | AR (0.74) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL11562791 | 0.84 | ALDH1A1 (0.72) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL7583434 | 0.82 | HPGD (0.70) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL30143812 | 0.82 | HPGD (0.78) | CYP3A4HPGDCYP2C19ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-1391327-B1 | Tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1542676-A4 | METHODS OF TREATING BENZODIAZEPINE SITE (BZD-S) ASSOCIATED SYNDROMES USING 2' HYDROXYFLAVONOIDS | PHARMACOGENETICS LTD (CN) | 2008-04-30 | — | — | EP | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| EP-1542676-A1 | METHODS OF TREATING BENZODIAZEPINE SITE (BZD-S) ASSOCIATED SYNDROMES USING 2' HYDROXYFLAVONOIDS | Phamacogenetics Limited (CN) | 2005-06-22 | — | — | EP | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| US-6740677-B2 | ANXIETY, CONVULSIONS | NATURON LIMITED (HK) | 2004-05-25 | — | — | US | disclosed |
| WO-2004016265-A1 | METHODS OF PREDICTING GABAA RECEPTOR EFFICACIES FOR FLAVONOID COMPOUNDS AND USES THEREFOR | PHAMACOGENETICS LIMITED (CN) | 2004-02-26 | — | — | WO | disclosed |
| WO-2004016266-A1 | METHODS OF TREATING BENZODIAZEPINE SITE (BZD-S) ASSOCIATED SYNDROMES USING 2’ HYDROXYFLAVONOIDS | PHAMACOGENETICS LIMITED (CN) | 2004-02-26 | — | — | WO | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| US-20040034092-A1 | Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2' hydroxyflavonoids | NATURON LIMITED (CN) | 2004-02-19 | — | — | US | disclosed |
| EP-1355898-A1 | METHOD FOR PRODUCING FLAVONE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-29 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| WO-2002060889-A1 | METHOD FOR PRODUCING FLAVONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | CYP3A4 17/4885HPGD 1949/4885CYP2C19 185/4885 |
| US-20040034092-A1 | Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2' hydroxyflavonoids | GABBR1, GABBR2, GABRB2 | CYP3A4 106/4885HPGD 350/4885CYP2C19 97/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | CYP3A4 3010/4885HPGD 558/4885CYP2C19 2389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.