Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827252 | 0.87 | L3MBTL1 (0.73) | L3MBTL1NPC1RAB9AHDAC4HDAC8 | |
| SCHEMBL6824235 | 0.82 | L3MBTL1 (0.65) | L3MBTL1NPC1RAB9AGLO1KMT2A | |
| SCHEMBL6827428 | 0.77 | L3MBTL1 (0.62) | L3MBTL1BRD4NPC1RAB9AGLO1 | |
| Methylamine SCHEMBL27666960 | 0.74 | MAOB (0.61) | NPC1RAB9AHDAC4HDAC8KMT2A | |
| SCHEMBL28102064 | 0.74 | CYP1A2 (0.72) | NPC1RAB9AHDAC4HDAC8KMT2A | |
| SCHEMBL458391 | 0.74 | CYP1A1 (0.64) | BRD4NPC1RAB9AHDAC4HDAC8 | |
| SCHEMBL29740761 | 0.74 | CYP1A1 (0.64) | BRD4NPC1RAB9AHDAC4HDAC8 | |
| SCHEMBL6824832 | 0.73 | L3MBTL1 (0.81) | L3MBTL1GLO1KMT2AMEN1GAA | |
| SCHEMBL6827244 | 0.73 | L3MBTL1 (0.81) | L3MBTL1GLO1KMT2AMEN1GAA | |
| SCHEMBL6827186 | 0.72 | L3MBTL1 (0.73) | L3MBTL1GLO1HSP90AA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |