Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824842 | 0.94 | GRM5 (0.34) | GRM5P2RX7HSD11B1KDM1ASCD5 | |
| SCHEMBL6829543 | 0.82 | PGR (0.43) | PTGDR2KCNH2HTR2AHTR2CHTR2B | |
| SCHEMBL6823828 | 0.77 | PGR (0.46) | — | |
| SCHEMBL6824341 | 0.76 | ALDH1A1 (0.45) | KDM4EALDH1A1HTT | |
| SCHEMBL11947631 | 0.70 | USP30 (0.47) | HSD11B1PTGDR2HSD11B2CYP19A1 | |
| SCHEMBL18696087 | 0.69 | CYP1B1 (0.46) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL6827239 | 0.68 | CYP1B1 (0.43) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL6827385 | 0.66 | MTOR (0.35) | KDM4EALDH1A1KCNH2 | |
| SCHEMBL9021665 | 0.66 | KDM4E (0.61) | GRM5KDM1AKDM4EALDH1A1HPGD | |
| SCHEMBL6924757 | 0.65 | P4HTM (0.34) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |