Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18161913 | 0.79 | KDM1A (0.48) | ATMDRD2HTR1AHTR2ADRD3 | |
| SCHEMBL1066184 | 0.79 | KDM1A (0.48) | ATMDRD2HTR1AHTR2ADRD3 | |
| SCHEMBL2606127 | 0.79 | QDPR (0.55) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL27481274 | 0.79 | DRD2 (0.58) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL21675821 | 0.79 | PARP10 (0.44) | PARP10ATMDRD2HTR1AHTR2A | |
| SCHEMBL18255078 | 0.79 | DRD2 (0.47) | PARP10ATMDRD2HTR1AHTR2A | |
| SCHEMBL28130860 | 0.79 | SLC18A3 (0.53) | ATMDRD2DRD3NPC1RAB9A | |
| SCHEMBL17529255 | 0.79 | ATM (0.44) | PARP10ATMDRD2HTR1AHTR2A | |
| SCHEMBL7344869 | 0.78 | SLC18A3 (0.55) | DRD2GRIN2BALDH1A1 | |
| SCHEMBL21746443 | 0.78 | KDM1A (0.45) | ATMHTR2AKDM1ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058727-A1 | SUBSTITUTED 3,5-DIHYDRO-4H-IMIDAZOL-4-ONES FOR THE TREATMENT OF OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |