Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 9/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20882044 | 0.87 | SLC18A3 (0.47) | SLC18A3GRIN2BDRD2SIGMAR1CYP2D6 | |
| SCHEMBL13068163 | 0.87 | SLC18A3 (0.47) | SLC18A3GRIN2BDRD2SIGMAR1CYP2D6 | |
| Tert-Butyl Formate SCHEMBL27584376 | 0.80 | DRD2 (0.42) | SLC18A3GRIN2BDRD2SIGMAR1CARM1 | |
| SCHEMBL6827484 | 0.78 | PARP10 (0.44) | GRIN2BDRD2ALDH1A1 | |
| SCHEMBL28130860 | 0.78 | SLC18A3 (0.53) | SLC18A3DRD2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL16312224 | 0.78 | TP53 (0.47) | CYP1A2 | |
| SCHEMBL27481274 | 0.78 | DRD2 (0.58) | SLC18A3DRD2MEN1KMT2A | |
| SCHEMBL19101372 | 0.77 | SLC18A3 (0.55) | SLC18A3GRIN2BDRD2SIGMAR1CYP2D6 | |
| SCHEMBL96849 | 0.77 | SLC18A3 (0.55) | SLC18A3GRIN2BDRD2SIGMAR1CYP2D6 | |
| SCHEMBL18123291 | 0.77 | GRIN2B (0.56) | SLC18A3GRIN2BDRD2SIGMAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555063-B1 | 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2020-09-16 | — | — | EP | disclosed |
| WO-2018108704-A1 | NEW 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-21 | — | — | WO | disclosed |
| EP-2057156-B1 | 2-METHYLMORPHOLINE PYRIDO-,PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS | KUDOS PHARM LTD (GB) | 2017-02-01 | — | — | EP | disclosed |
| EP-3091012-A1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | Centrexion Therapeutics Corporation (US) | 2016-11-09 | — | — | EP | disclosed |
| EP-2379525-B1 | CYCLIC PYRIMIDIN-4-CARBOXAMIDES AS CCR2 RECEPTOR ANTAGONISTS FOR TREATMENT OF INFLAMMATION, ASTHMA AND COPD | BOEHRINGER INGELHEIM INT (DE) | 2015-07-29 | — | — | EP | disclosed |
| EP-2816040-A1 | Process for the production of CCR2 receptor antagonists and intermediates thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-24 | — | — | EP | disclosed |
| EP-2813503-A1 | A process for the production of new CCR2 receptor antagonists and intermediates thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-17 | — | — | EP | disclosed |
| US-20120329661-A1 | Isotope Labeling-Assisted Quantification (iLAQ) of Biological Compounds | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2012-12-27 | — | — | US | disclosed |
| CN-101696187-B | Synthesizing method of N-substituent-1,2,3,6-tetrahydropyridine | XUZHOU COLLEGE IND TECHNOLOGY | 2011-09-07 | — | — | CN | disclosed |
| CN-101696187-A | Synthesizing method of N-substituent-1,2,3,6-tetrahydropyridine | XUZHOU COLLEGE OF IND TECHNOLO | 2010-04-21 | — | — | CN | disclosed |
| WO-1993008206-A1 | NOVEL 2,6-DISUBSTITUTED PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-04-29 | — | — | WO | disclosed |
| US-5013742-A | Analgesics, Anesthetics, Narcotic Antagonists | BOC, INC. (US) | 1991-05-07 | — | — | US | disclosed |
| US-4921864-A | 4-Phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds | BOC, INC. (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0315405-A1 | 4-phenyl-4-(N-(2-fluorophenyl)amido) piperidine derivatives | Ohmeda Pharmaceutical Products Division Inc. (US) | 1989-05-10 | — | — | EP | disclosed |
| US-4791121-A | ANALGESICS | THE BOC GROUP, INC. (US) | 1988-12-13 | — | — | US | disclosed |
| US-4694016-A | ISOXAZOLES, PARASITIC WORMS; MAMMALS BIRDS | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0144853-A2 | Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| EP-0042570-B1 | 20-DEOXYROSARAMICIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1983-10-19 | — | — | EP | disclosed |
| EP-0042570-A1 | 20-Deoxyrosaramicin derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4279896-A | Novel 20-imino macrolide antibacterial agents | SCHERING CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329661-A1 | Isotope Labeling-Assisted Quantification (iLAQ) of Biological Compounds | SRMS, QPCTL, NUP155 | SLC18A3 3176/4885GRIN2B 4537/4885DRD2 2187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.