Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | PNLIP | P16233 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 6/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528683 | 0.89 | ALDH1A1 (0.47) | TSHRPNLIPLMNACYP1A2CYP2C19 | |
| SCHEMBL10295292 | 0.87 | MGLL (0.56) | TSHRLMNASMN1; SMN2TP53PLA2G4B | |
| SCHEMBL7529405 | 0.86 | TSHR (0.46) | TSHRLMNACYP1A2CYP2C19ESR1 | |
| SCHEMBL3626125 | 0.85 | TP53 (0.58) | TSHRMAPK1TP53PLA2G4B | |
| SCHEMBL8840752 | 0.85 | TP53 (0.50) | TSHRTP53PLA2G4B | |
| SCHEMBL1263538 | 0.84 | ESR1 (0.54) | TSHRPNLIPLMNACYP1A2CYP2C19 | |
| SCHEMBL29051387 | 0.84 | ESR1 (0.54) | TSHRPNLIPLMNACYP1A2CYP2C19 | |
| SCHEMBL5609102 | 0.84 | TP53 (0.53) | TSHRTP53PLA2G4B | |
| SCHEMBL9061631 | 0.84 | TP53 (0.60) | TSHRTP53PLA2G4B | |
| SCHEMBL9061850 | 0.82 | PARP10 (0.53) | TSHRLMNAMAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370512-A4 | NOVEL MESOGENS | SOUTHWEST RES INST (US) | 2004-04-14 | — | — | EP | disclosed |
| EP-1370512-A2 | NOVEL MESOGENS | Southwest Research Institute (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002059227-A2 | NOVEL MESOGENS | SOUTHWEST RESEARCH INSTITUTE (US) | 2002-08-01 | — | — | WO | disclosed |