Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11382754 | 0.99 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP1A2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL684271 | 0.88 | TSHR (0.54) | MAOBMAPTLMNAHTTTSHR | |
| Hydrochloric Acid SCHEMBL11384998 | 0.87 | TSHR (0.53) | MAOBMAPTLMNAHTTTSHR | |
| SCHEMBL683888 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2MAOBMAPTTP53LMNA | |
| Hydrochloric Acid SCHEMBL11381649 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2MAOBMAPTTP53LMNA | |
| SCHEMBL683962 | 0.83 | ADORA2B (0.62) | SMN1; SMN2MAOBLMNAHTTTSHR | |
| Hydrochloric Acid SCHEMBL11388923 | 0.82 | ADORA2B (0.61) | SMN1; SMN2MAOBLMNAHTTTSHR | |
| Diethylamine SCHEMBL11385881 | 0.82 | CYP1A2 (0.54) | SMN1; SMN2CYP1A2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL683542 | 0.82 | NCOA3 (0.54) | SMN1; SMN2MAOBMAPTLMNAHTT | |
| SCHEMBL682765 | 0.81 | MAOB (0.49) | MAOBTP53ALDH1A1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299832-A | Substituted theophylline compounds | FISONS LIMITED (GB) | 1981-11-10 | — | — | US | claimed |
| EP-0011399-A1 | N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1980-05-28 | — | — | EP | claimed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | SMN1; SMN2 907/4885CYP1A2 4049/4885CYP2C19 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.