SCHEMBL6828058

SCHEMBL6828058

O=C(O)c1ccccc1Sc1ccc([N+](=O)[O-])c2c1C(=O)c1c(Sc3ccccc3C(=O)O)ccc([N+](=O)[O-])c1C2=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.60
GSTM2 P28161 1/20 0.60
MAPT P10636 4/20 0.53
LMNA P02545 2/20 0.53
HTT P42858 1/20 0.53
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
SLC6A2 P23975 2/20 0.48
SLC6A4 P31645 2/20 0.48
SLC6A3 Q01959 2/20 0.48
GAA P10253 1/20 0.48
TSHR P16473 2/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HIF1A Q16665 1/20 0.45
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5186500 0.85 POLB (0.57) GSTP1GSTM2MAPTLMNAKDM4E
SCHEMBL2028311 0.81 SLC6A2 (0.68) GSTP1GSTM2MAPTLMNAHTT
SCHEMBL1645800 0.78 MAPT (0.60) GSTP1GSTM2MAPTLMNAHTT
SCHEMBL6825619 0.78 MAPT (0.57) GSTP1GSTM2MAPTLMNAKDM4E
SCHEMBL29484401 0.77 TXNRD1 (0.67) GSTP1GSTM2MAPTLMNAHTT
SCHEMBL1645182 0.77 TXNRD1 (0.67) GSTP1GSTM2MAPTLMNAHTT
SCHEMBL4003277 0.77 LMNA (0.68) GSTP1GSTM2MAPTLMNAHTT
SCHEMBL17080224 0.77 LMNA (0.61) GSTP1GSTM2MAPTLMNAHTT
SCHEMBL28643490 0.76 TSHR (0.59) MAPTLMNAKDM4EALDH1A1MEN1
SCHEMBL17080274 0.76 LMNA (0.63) GSTP1GSTM2MAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040195552-A1 useful as powders or pellets for incorporation into a variety of thermoplastic resins; diacidic anthraquinone compounds WEAVER MAX ALLEN (US) 2004-10-07 US disclosed
US-6776930-B2 POLYMER BONDED TO DYE EASTMAN KODAK COMPANY 2004-08-17 US disclosed
US-20010023938-A1 Polymer bonded to dye ALLEN MAX (US) 2001-09-27 US disclosed
US-6197223-B1 REACTING DIACIDIC MONOMER HAVING FORMULA H--A--H, COMPRISING 1 TO 100 MOLE % OF LIGHT-ABSORBING MONOMER HAVING A LIGHT ABSORPTION MAXIMUM BETWEEN 300 NM AND 1200 NM AND 99-0 MOLE % OF A NON-LIGHT ABSORBING MONOMER WITH ORGANIC COMPOUND EASTMAN CHEMICAL COMPANY 2001-03-06 US disclosed
EP-0948570-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1999-10-13 EP disclosed
WO-1998023690-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1998-06-04 WO disclosed