Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.51 |
| ▸ | FEN1 | P39748 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421198 | 0.92 | CES2 (0.62) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL30758862 | 0.87 | CES2 (0.69) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL11248287 | 0.87 | CES2 (0.69) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL28821922 | 0.86 | CES2 (0.59) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL8889322 | 0.85 | KMT2A (0.68) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL21383255 | 0.83 | ERCC5 (0.72) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL2278242 | 0.82 | CES2 (0.62) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL2130116 | 0.82 | CES2 (0.62) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL30626936 | 0.82 | CES2 (0.62) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL4722288 | 0.81 | ALDH1A1 (0.69) | CES2CES1NPC1RAB9AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |