Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 2/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30758862 | 0.95 | CES2 (0.69) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL11248287 | 0.95 | CES2 (0.69) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL1421198 | 0.90 | CES2 (0.62) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL8269548 | 0.90 | HSD11B1 (0.64) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL21383255 | 0.87 | ERCC5 (0.72) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL2130116 | 0.86 | CES2 (0.62) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL2278242 | 0.86 | CES2 (0.62) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL30626936 | 0.86 | CES2 (0.62) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL6828059 | 0.85 | CES2 (0.57) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL3846484 | 0.85 | PARP1 (0.67) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089988-B1 | FLUOROPHENYL RESIN COMPOUNDS | AVENTIS PHARMA INC (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |