Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CLPP | Q16740 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730533 | 0.85 | KMT2A (0.56) | MEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL22147836 | 0.81 | SIGMAR1 (0.50) | SIGMAR1MEN1KMT2AL3MBTL1CMA1 | |
| SCHEMBL6732110 | 0.77 | KMT2A (0.66) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL3421964 | 0.74 | ALDH1A1 (0.46) | SIGMAR1MEN1KMT2AL3MBTL1CMA1 | |
| SCHEMBL34474111 | 0.73 | KMT2A (0.52) | SIGMAR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL24992399 | 0.72 | KMT2A (0.61) | SIGMAR1MEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL5660883 | 0.71 | LMNA (0.44) | SIGMAR1MEN1KMT2APKMLMNA | |
| SCHEMBL6828052 | 0.71 | SIGMAR1 (0.56) | SIGMAR1MEN1KMT2ACMA1PKM | |
| SCHEMBL13201398 | 0.69 | KMT2A (0.58) | SIGMAR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL29137409 | 0.69 | KMT2A (0.58) | SIGMAR1MEN1KMT2AL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004075847-A2 | METHODS AND COMPOUNDS FOR THE TREATMENT OF Aß ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS | MESSAGE PHARMACEUTICALS, INC. (US) | 2004-09-10 | — | — | WO | disclosed |