Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634919 | 0.86 | AKR1C3 (0.50) | SMN1; SMN2KDM4EALDH1A1POLBLMNA | |
| SCHEMBL23292610 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL29955976 | 0.84 | TRIM24 (0.61) | SMN1; SMN2KDM4EALDH1A1POLBLMNA | |
| SCHEMBL548189 | 0.84 | TRIM24 (0.61) | SMN1; SMN2KDM4EALDH1A1POLBLMNA | |
| SCHEMBL2801319 | 0.82 | ALDH1A1 (0.39) | SMN1; SMN2KDM4EALDH1A1POLBLMNA | |
| SCHEMBL15251706 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2KDM4EALDH1A1POLBLMNA | |
| SCHEMBL28596875 | 0.78 | CA12 (0.55) | ALDH1A1POLBHSD17B10TYRMEN1 | |
| SCHEMBL383820 | 0.77 | ALDH1A1 (0.66) | SMN1; SMN2KDM4EALDH1A1POLBLMNA | |
| SCHEMBL8965812 | 0.77 | ABCG2 (0.66) | SMN1; SMN2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL6828133 | 0.77 | LCK (0.41) | SMN1; SMN2KDM4EALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902330-B2 | Protein kinase inhibitors and methods for identifying same | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-03-08 | — | — | US | disclosed |