Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828537 | 0.87 | MAPT (0.58) | LMNAUSP2RAB9AHTTALDH1A1 | |
| SCHEMBL6828188 | 0.82 | MAPT (0.55) | LMNAUSP2RAB9AHTTALDH1A1 | |
| SCHEMBL6828204 | 0.79 | SMN1; SMN2 (0.70) | LMNARAB9AHTTALDH1A1HPGD | |
| SCHEMBL6825121 | 0.79 | LMNA (0.54) | LMNAUSP2RAB9AHTTALDH1A1 | |
| SCHEMBL6828203 | 0.78 | MAPT (0.60) | LMNARAB9AHTTALDH1A1HPGD | |
| SCHEMBL6828519 | 0.78 | RXFP1 (0.58) | LMNARAB9AHTTALDH1A1HPGD | |
| SCHEMBL6828515 | 0.78 | MAPT (0.52) | LMNAUSP2RAB9AHTTALDH1A1 | |
| SCHEMBL6825632 | 0.78 | MAPT (0.52) | LMNAUSP2RAB9AHTTALDH1A1 | |
| SCHEMBL6825638 | 0.77 | MAPT (0.47) | LMNAUSP2RAB9AHTTALDH1A1 | |
| SCHEMBL6825618 | 0.76 | MAPT (0.60) | LMNAUSP2RAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138269-A1 | Substituted pyrroles as kinase inhibitors | SUGEN, INC. | 2004-07-15 | — | — | US | claimed |
| US-20040138269-A1 | Substituted pyrroles as kinase inhibitors | SUGEN, INC. | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138269-A1 | Substituted pyrroles as kinase inhibitors | PHKG1, PHKG2, MAP3K20 | LMNA 2490/4885USP2 3147/4885RAB9A 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.