Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3625349 | 0.89 | NUDT1 (0.41) | NUDT1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL8795406 | 0.87 | NUDT1 (0.51) | NUDT1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL14719221 | 0.86 | KMT2A (0.50) | NUDT1MAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL9345248 | 0.86 | KMT2A (0.47) | NUDT1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL30579455 | 0.78 | NPC1 (0.69) | NUDT1MAPTSMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL4270430 | 0.78 | MAPT (0.39) | TLR8MAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL22576042 | 0.76 | MAPT (0.38) | TLR8MAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL6826174 | 0.76 | MAPT (0.45) | TLR8MAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL1577067 | 0.76 | NUDT1 (0.37) | NUDT1POLBMEN1CYP1A2CYP2C9 | |
| SCHEMBL30579446 | 0.74 | NUDT1 (0.53) | NUDT1CDK1CCNB1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111000-A2 | PIPERIDYL DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2004-12-23 | — | — | WO | disclosed |