Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828247 | 0.86 | NUDT1 (0.44) | KMT2ANUDT1CDK1CCNB1CCNA2 | |
| SCHEMBL3625349 | 0.80 | NUDT1 (0.41) | KMT2ANUDT1CDK1CCNB1CCNA2 | |
| SCHEMBL8795406 | 0.78 | NUDT1 (0.51) | KMT2ANUDT1CDK1CCNB1CCNA2 | |
| SCHEMBL8448250 | 0.78 | KMT2A (0.51) | KMT2ANUDT1ADORA2APIK3CASMN1; SMN2 | |
| SCHEMBL14719221 | 0.77 | KMT2A (0.50) | KMT2ANUDT1MAPTSMN1; SMN2POLB | |
| SCHEMBL8446516 | 0.73 | NPC1 (0.54) | KMT2ANUDT1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL1427693 | 0.71 | — | — | |
| SCHEMBL7806796 | 0.71 | KMT2A (0.45) | KMT2ANUDT1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL30579455 | 0.70 | NPC1 (0.69) | KMT2ANUDT1MAPTADORA2ASMN1; SMN2 | |
| SCHEMBL9340477 | 0.70 | KMT2A (0.45) | KMT2ANUDT1CDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378089-B1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AG (DE) | 1994-06-29 | — | — | EP | disclosed |
| EP-0378092-B1 | Herbicidal sulfonyl ureas, process for preparing them and their use | BASF AG (DE) | 1994-05-11 | — | — | EP | disclosed |
| US-5011927-A | Preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| EP-0378089-A1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF Aktiengesellschaft (DE) | 1990-07-18 | — | — | EP | disclosed |
| EP-0378092-A1 | Herbicidal sulfonyl ureas, process for preparing them and their use | BASF Aktiengesellschaft (DE) | 1990-07-18 | — | — | EP | disclosed |